Showing posts from November, 2018

Heart failure and albuminuria associations across nearly 400,000 UK Biobank subjects now available in the CVDKP

Two new datasets now bring associations for heart failure and albuminuria from large UK Biobank subject pools to the Cardiovascular Disease Knowledge Portal (CVDKP). Both studies revealed important insights about the etiology of different aspects of cardiovascular disease. And the results of both studies are available now in the CVDKP--both integrated into the Portal, and as files of summary statistics for download.

The study of heart failure associations (Aragam et al. (2018), Circulation) looked at associations both with heart failure from any cause and with a more refined phenotype, nonischemic cardiomyopathy (NICM), defined as left ventricular dysfunction without coronary artery disease. The loci significantly associated with all-cause heart failure were predominantly those already known to be associated with heart failure risk factors, such as coronary artery disease and atrial fibrillation. However, refining the phenotype to NICM revealed a different spectrum of associations, ov…

See you at AHA!

This weekend, cardiovascular researchers from around the globe will be meeting in Chicago for the 2018 Scientific Sessions of the American Heart Association. For the Cardiovascular Disease Knowledge Portal team, this is an opportunity to meet and talk with the geneticists and biologists who use the site and get your input on how we can improve it.

Please come visit us at booth #2249 in the Exhibit Hall! We'll be there on Saturday, Nov. 10 from 11am-5pm; on Sunday, Nov. 11 from 10am-4:30pm; and on Monday, Nov. 12 from 10am-3pm.